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Cyclodextrin metabolism

- Apr 06, 2018 -

Cyclodextrins enter the body in two ways: one is the intestine and the other is the parenteral. The two ways of cyclodextrins metabolism in the human body is very different, the first way is oral, the study found that cyclodextrin in the human intestine will be partially decomposed in the colon to generate carbon dioxide and water discharge, The time is 4-8 hours after oral administration. The second method is injection. Cyclodextrins are not absorbed by cells and excreted through the kidneys through the human circulatory system. These two methods fully demonstrate that cyclodextrin is relatively stable in the human body, and most of them are excreted in a complete form without causing damage to the body.

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