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Cyclodextrins and Antitumor Natural Products

- Jun 04, 2018 -

There are a wide variety of natural products that have anti-tumor activity. Most of them are difficult to dissolve in water, are easily oxidized, and are sensitive to light and heat, which limits their clinical application. Studies have found that cyclodextrins and their derivatives can form inclusion complexes with natural products that are anti-tumor active, significantly improving the solubility and stability of these natural products, and their biological activity is not affected. By preparing an antitumor natural product-cyclodextrin supramolecular system, an anti-tumor natural product pharmaceutical preparation with high water-solubility, high drug activity and low toxicity can be prepared.

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