Phytosterol is a natural active substance, which can reduce the total cholesterol and low density lipoprotein cholesterol in serum. It has a wide range of applications in food, cosmetics, medicine and other fields, and has a very good market prospect. However, the water insolubility of phytosterols limits its application in food industry. Therefore, the development of water-soluble phytosterols to solve the problem of water-solubility can promote the development of related functional foods and other industries.
Hydroxypropyl beta cyclodextrin (HPBD) is an excellent pharmaceutical adjuvant. It is not only water-soluble, but also non-toxic and harmless. It is stable to alkali, light and heat. It is a very good inclusion material.Using Hydroxypropyl beta cyclodextrin inclusion phytosterols, the nonpolar cavity for sterol nonpolar carbon chain section provides a good space, then the inherent hydroxyl groups of the sterol part exposed side, and inherent in cyclodextrin hydroxyl increased overall hydrophilic properties, thus improving the sterol solubility in water.