Name: Pharma grade hydroxypropyl beta cyclodextrin
Synonym:Pharma grade hydroxypropyl betadex
CAS No.: 128446-35-5
Molecular formula: C42H70-nO35(C3H8O2)n
Molecular weight: 1134.98+58n
DMF No.: 030168
Standard: USP40-NF35 / CP2015
Qaulity: Pharma grade
Application of hydroxypropyl beta cyclodextrin in pharmaceutical field:
1. To increase the solubility of medicine and biological availability
2. To improve the bio availability of drugs.
3. To adjust or control the releasing of drugs.
4. To decrease the toxicities of drugs.
5. To improve the stabilities of drugs.
Clarity of Solution
A 30%w/v solution in water is clear and essentially free from particles of foreign matter
Same absorption bands as USP betadex sulfobutyl ether sodium RS
Identify test are positive for Sodium
the retention time of the major peak of sample solution corresponds to the standard solution
Average Degree of Substitution
Water solution pH
pH of 30%w/v solution in water is 4.0-6.8
Disodium bis-(4-sulfobtyl) ether
TAMC ( cfu/g)
TYMC ( cfu/g)
Packaging and storage
Preserve in well-closed containers, and store at room temperature. Protect from moisture.
Conclusion: According to USP40-NF35 standard, the product is Qualified.
Storage: at room temperature, in tightly closed container.