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Practical characteristics of Betadex Sulfobutyl Ether Sodium

- May 29, 2018 -

Betadex Sulfobutyl Ether Sodium can well combine with drug molecules to form non covalent complexes, thus improving drug stability, water solubility, safety, reducing renal toxicity, easing drug hemolysis, controlling drug release rate, and masking bad odors.

1, Solubilization:

Neutral, positive and negative drugs can be effectively combined with sulfonylcyclodextrin, which can increase the solubility of different compounds in the raw material by 10 to 25000 times.

2, The convenience of drug delivery:

Sodium sulfonylbutane cyclodextrin has good biocompatibility and can be injected, orally, ophthalmic, nasal, topical and inhaled.

3. Good security:

Usually, it can be quickly and completely eliminated from the kidneys after administration. In vitro experiments and in vivo acute, subacute and chronic toxicity studies provide safe data and approval for human pharmaceutical preparations.

4. Good stability:

The interaction with sulfonylcyclodextrin sodium can provide a beneficial protection environment for the raw material in its oil parent cavity, while the water solubility and stability of the hydrophilic surface provide excellent solubility.


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