Betadex sulfobutyl ether sodium is the product that β-Cyclodextrin 6 (also including 2, 3) OH is substituted by Sulfobutyl. It can be divided into single substitution, multiple substitution and total 6 substitutionβ-Cyclodextrin. The molecular formula is therefore different. Sulfobutyl Ether-Beta-Cyclodextrin has special affinity and inclusion for nitrogen containing. drugs.
Betadex sulfobutyl ether sodium(SBE-β-CD)is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
Betadex sulfobutyl ether sodium(SBE-β-CD)has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.