Berberine has been used as an over-the-counter drug in the treatment of diarrhea, but modern pharmacological studies have proved that berberine has a significant anti-heart failure, anti-arrhythmia, reduce cholesterol, anti-vascular smooth muscle proliferation, improve insulin resistance. Antiplatelet, anti-inflammatory and other functions may be widely used in cardiovascular system and nervous system diseases, and will be paid more and more attention. Berberine absorption is extremely poor, almost stay in the gastrointestinal tract, not easy to enter the blood through the gastrointestinal tract. Taking full advantage of the inclusion advantage of its own product Hp- β -CDC, Zhiyuan biology has carried out a good inclusion cooperation with berberine, because Hp- β -CDC is sweet. Therefore, inclusion of berberine with hydroxypropyl beta-cyclodextrin can reduce the bitter taste of berberine to a large extent, and the solubility of berberine in water after inclusion can be greatly improved, thus increasing the utilization rate of berberine. By putting a sugar coat on berberine, it was given a new life.