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Pharmaceutical Application Of Betadex Sulfobutyl Ether Sodium

- Oct 24, 2018 -

Applied to injectable drugs

The main purpose is to improve the solubility of insoluble drugs, so that the drug can be delivered quickly and reach the required dosage during injection, reduce the irritation of injection to the injection site, improve the stability of drugs in solution state, ease the hemolysis of drugs, and improve the safety of drug use.

Applied to oral drugs

By increasing the solubility of the drug to increase the biological activity of the drug, by modifying the drug release site to increase the stability of the drug or prolong the drug release time in the gastrointestinal tract, reduce drug irritation to local tissues, masking the unpleasant odor of some drugs.

Application in nasal administration

The mechanism of drug delivery is to increase the permeability of nasal mucosa, improve the solubility and stability of drugs, and improve the metabolic rate of drugs at the target site.

Applied to eye drugs

Betadex sulfobutyl ether sodium mainly increases the solubility and stability of poorly water-soluble drugs, and reduces irritation to cornea.


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