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Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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Cyclodextrin Inclusion Function: Spray Drying

- Jul 04, 2018 -

The state of drugs is solid, liquid and gas. In general, the state of solid state is most widely used, and liquid drugs are mostly volatile, and it is easy to cause the loss of effective components during preparation and storage.

Cyclodextrin inclusion technology is a major breakthrough in the powder preparation of liquid drugs. For many liquid drugs, the use of cyclodextrin inclusion can make it powder. While changing the drug morphology, it can also solve the defects such as poor solubility in water, poor stability and so on. The drug should be increased to a great extent. Use the scope. Especially in the traditional Chinese medicine industry, the powder preparation of volatile oil can be made into traditional Chinese medicine tablets, capsules, granules, granules and other forms, and changes the deficiency of the traditional preparation of traditional Chinese medicine, such as single dosage form, inaccurate dose, unstable effect and so on.

In addition, when liquid vitamin D or E1 is combined with beta cyclodextrin, its stability can be greatly improved, and various forms of solid preparations can be made. With the study of cyclodextrin derivatives, the better medicinal excipients are produced. Hydroxypropyl dicyclodextrin and sulfonyl ether dicyclodextrin sodium salt are two highly representative cyclodextrin derivatives. They are far superior to the cyclodextrin in the solubilization effect and the improvement of new dosage forms, especially the advanced drying techniques. Application of technology, spray drying, freeze drying and other technologies also make liquid pharmaceutical powder technology more and more widely used.

Shandong Binzhou Zhiyuan biological science and Technology Co., Ltd. is a scientific and technological company focusing on the application, development and innovation of cyclodextrin and cyclodextrin derivatives. The company has strong technical force and close cooperation with the first-class universities and research institutes at home and abroad, such as Shandong University and CAS. At present, the domestic cyclodextrin industry has the largest variety and the most comprehensive professional R & D production enterprise. Hydroxypropyl beta cyclodextrin and Betadex Sulfobutyl Ether Sodium are our two main products. They are fully qualified and welcome all walks of life to negotiate.


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